Rheumatoid mob caj dab yog ib tug mob inflammatory kab mob uas cim los ntawm ob leeg mob, o thiab puas. Txawm hais tias cov tshuaj, xws li cov tshuaj steroids, tshuaj tiv thaiv kab mob thiab tshuaj tiv thaiv kab mob, tuaj yeem pab ua kom qeeb kev puas tsuaj thiab txo qhov mob, lawv muaj kev phiv thiab tsis ua tiav. Tam sim no, cov kws tshawb fawb qhia hauv ACS 'Nano Cov Ntawvtau tsim magnesium-based micromotors propelled los ntawm hydrogen npuas, uas txhim kho cov tsos mob rheumatoid mob caj dab thaum txhaj rau hauv cov pob qij txha ntawm nas.
Cov kws tshawb fawb tau txuas cov kab mob rheumatoid kev loj hlob mus rau ntau tshaj ntawm cov pa oxygen reactive (ROS). ROS tuaj yeem oxidize thiab degrade pob txha mos thiab pob txha, nrog rau qhib qhov kev qhia ntawm inflammatory cytokines. Ib hom kev kho tshiab, cov pa roj hydrogen, tuaj yeem cuam tshuam ROS thiab txo qis cytokine theem thaum muab rau cov neeg mob hauv cov dej haus. Txawm li cas los xij, cov pa roj tsis zoo hauv cov kua hauv lub cev thiab tshem tawm sai sai thaum muab qhov ncauj, txwv nws cov teebmeem kev kho mob. Fei Peng, Yingfeng Tu, Yingjia Li thiab cov npoj yaig xav nrhiav txoj hauv kev los tsim thiab xa cov roj hydrogen ncaj qha rau hauv qhov sib koom ua ke.
Cov kws tshawb fawb ua raws lawv cov kab ke ntawm magnesium-based micromotors -- me me spheres uas hnov mob nrog dej los tsim cov npuas hydrogen, uas ua rau lub cev muaj zog. Lawv coated lub micromotors nrog hyaluronic acid, ib tug sib koom ua ke lubricant, tawm hauv me me qhib rau magnesium kom hnov mob nrog dej. Thaum muab tso rau hauv cov kua dej sib xyaw ua ke, cov micromotors tau pom ntev, tso tawm cov npuas hydrogen thiab tuaj yeem txav mus los ntawm lawv tus kheej. Pab neeg no tau txhaj cov micromotors rau hauv cov pob qij txha ntawm cov nas uas tau ua tus qauv tsiaj ntawm rheumatoid mob caj dab thiab siv ultrasound kom pom lawv. Piv nrog rau cov nas uas tsis tau txhaj tshuaj, cov nas kho tau pom cov paws tsawg dua, txo cov pob txha yaig thiab qis qis ntawm cov cytokines. Txawm hais tias cov micromotors tseem yuav tsum tau kuaj hauv tib neeg, lawv pom muaj peev xwm zoo rau kev kho mob rheumatoid mob caj dab thiab lwm yam kab mob inflammatory, cov kws tshawb fawb hais.
Nco tseg:Cov ntsiab lus tuaj yeem hloov kho rau style thiab ntev.